Clinical Study References

# Therapeutic Application Author and Title Journal Details Status Link
1 Stress & Anxiety Chandrasekhar, K., Kapoor, J., & Anishetty, S. (2012). A prospective, randomized double-blind, placebo-controlled study of the safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian journal of psychological medicine Published Link
2 Male Sexual Function Ambiye, V. R., Langade, D., Dongre, S., Aptikar, P., Kulkarni, M., & Dongre, A. (2013). Clinical Evaluation of the Spermatogenic Activity of the Root Extract of Ashwagandha (Withania somnifera) in Oligospermic Males: A Pilot Study. Evidence-based complementary and alternative medicine Published Link
3 Muscle Strength and Recovery Wankhede, S., Langade, D., Joshi, K., Sinha, S. R., & Bhattacharyya, S. (2015). Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial. Journal of the International Society of Sports Nutrition Published Link
4 Sexual Function in Women Dongre, S., Langade, D., & Bhattacharyya, S. (2015). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Improving Sexual Function in Women: A Pilot Study. BioMed research international Published Link
5 Cardiorespiratory Endurance Choudhary, B., Shetty, A., & Langade, D. G. (2015). Efficacy of Ashwagandha (Withania somnifera [L.] Dunal) in improving cardiorespiratory endurance in healthy athletic adults. Ayu Published Link
6 Memory and Cognition Choudhary, D., Bhattacharyya, S., & Bose, S. (2017). Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. Journal of dietary supplements Published Link
7 Body Weight Management Choudhary, D., Bhattacharyya, S., & Joshi, K. (2017). Body Weight Management in Adults Under Chronic Stress Through Treatment with Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial. Journal of evidence-based complementary & alternative medicine Published Link
8 Subclinical Hypothyroidism Sharma, A. K., Basu, I., & Singh, S. (2018). Efficacy and Safety of Ashwagandha Root Extract in Subclinical Hypothyroid Patients: A Double-Blind, Randomized Placebo-Controlled Trial. Journal of alternative and complementary medicine Published Link
9 Sleep and Anxiety Langade, D., Kanchi, S., Salve, J., Debnath, K., & Ambegaokar, D. (2019). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double-blind, Randomized, Placebo-controlled Study. Cureus Published Link
10 Stress & Anxiety Salve, J., Pate, S., Debnath, K., & Langade, D. (2019). Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus Published Link
11 Elderly Health Kelgane, S. B., Salve, J., Sampara, P., & Debnath, K. (2020). Efficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study. Cureus Published Link
12 Sleep and Anxiety Langade, D., Thakare, V., Kanchi, S., & Kelgane, S. (2020). Clinical evaluation of the pharmacological impact of ashwagandha root extracts on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study. Journal of Ethnopharmacology Published Link
13 Safety Verma, N., Gupta, S. K., Tiwari, S., & Mishra, A. K. (2021). Safety of Ashwagandha Root Extract: A Randomized, Placebo-Controlled, Study in Healthy Volunteers. Complementary therapies in medicine Published Link
14 Cardiorespiratory Endurance Tiwari, S., Gupta, S. K., & Pathak, A. K. (2021). A double-blind, randomized, placebo-controlled trial on the effect of Ashwagandha (Withania somnifera Dunal.) root extract in improving cardiorespiratory endurance and recovery in healthy athletic adults. Journal of Ethnopharmacology Published Link
15 Perimenopause Gopal, S., Ajgaonkar, A., Kanchi, P., Kaundinya, A., Thakare, V., Chauhan, S., & Langade, D. (2021). Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study. Journal of obstetrics and gynecology research Published Link
16 Male Sexual Function Effect of Ashwagandha root extract on sexual function and testosterone levels in males: A randomized, double-blind, placebo-controlled study. Health Science Reports Published Link
17 Female Sexual Function Ajgaonkar A, Jain M, Debnath K (2022). Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study. Cureus Published Link
18 Skin Health Narra K, Naik S K, Ghatge A S (2023). A Study of Efficacy and Safety of Ashwagandha (Withania somnifera) Lotion on Facial Skin in Photoaged Healthy Adults. Cureus Published Link
19 Muscle Strength and Endurance Verma N, Gupta SK, Patil S et al. (2023). Effects of Ashwagandha (Withania somnifera) standardized root extract on physical endurance and VO2max in healthy adults preforming resistance training: An eight-week, prospective, randomized, double-blind, placebo-controlled study. F1000 Published Link
20 Recovery and Testosterone Verma N, Gupta SK, Tiwari S, Mishra AK, Thakare V, Patil S. (2023). Effect of Ashwagandha Root Extract on Serum Testosterone and Muscle Recovery in Strength Training. IJPMR Published Link
21 Hair Health Yerram, C., Jillella, A., & Reddy, V. (2023). Effects of Withania somnifera root extract serum application on hair health in healthy adults: A prospective, double-blind, randomized, parallel, placebo-controlled study. Journal of Ayurveda and Integrative medicine Published Link
22 Memory and Cognition - Adults Kale, S., Lopresti, A., Suri, R., Garg, N., & Langade, D. (2024). Safety and Efficacy of Ashwagandha Root Extract on Cognition, Energy and Mood Problems in Adults: Prospective, Randomized, Placebo-Controlled Study. Journal of Psychoactive Drugs Published Link
23 Female Sexual Function Mutha, A. S., Mutha, S. A., Tejuja, A. H., & Langade, D. K. (2025). Efficacy and safety of ashwagandha root extract on sexual health in healthy women: findings of a prospective, randomized, double-blind, placebo-controlled study. Cogent Psychology Published Link
24 Male Sexual Function Mutha, A. S., Mutha, S. A., Tejuja, A. H., Beldar, A. S., Mulay, A. M., & Langade, D. (2025). Efficacy and safety of eight-week therapy with Ashwagandha root extract in improvement of sexual health in healthy men: Findings of a prospective, randomized, double-blind, placebo-controlled study. Journal of Ayurveda and Integrative medicine Published Link
25 Recovery and Muscle Strength in Female Athletes Coope, O. C., Reales Salguero, A., Spurr, T., Páez Calvente, A., Domenech Farre, A., Jordán Fisas, E., Lloyd, B., Gooderick, J., Abad Sangrà, M., & Roman-Viñas, B. (2025). Effects of Root Extract of Ashwagandha (Withania somnifera) on Perception of Recovery and Muscle Strength in Female Athletes. European journal of sport science Published Link
26 Body Composition and Blood Health Indices in Professional Wrestlers Długołęcka, B., Jówko, E., Kotowska, J. & Gierczuk, D. (2023). Effects of Ashwagandha (Withania Somnifera) Supplementation on Body Composition and Blood Health Indices in Professional Wrestlers. Polish Journal of Sport and Tourism Published Link